From Southern California:
I-5 North to 99 North (toward Bakersfield)
99 North to 41 North (toward Fresno)
41 North to Oakhurst

From The Bay Area:
580 East to I-5 South (toward Fresno)
I-5 South to 132 East (toward Modesto)
132 East to 99 South (toward Merced)
99 South to 140 East (toward Mariposa)
140 East to 49 South (toward Oakhurst)
49 South to Oakhurst